Introduction: physical activity is closely related to mortality and respiratory status for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Pulmonary rehabilitation (PR) programs have been shown to improve the level of physical activity in COPD patients. There are no specific studies on patients with bronchiectasis.
Objectives: study the effect of PR on physical activity over 12 weeks, in comparison with PR plus a hyperproteic supplement enriched in beta-hydroxy-beta-methylbutyrate (HMB) in patients with non-CF bronchiectasis.
Material and methods: prospective, randomized study in which a structured PR program is applied in bronchiectasis patients for three months. Additionally, one of the groups received a hyperproteic supplement with HMB. The degree of physical activity was evaluated at baseline and after three and six months using the wGT3X (ActiGraph) accelerometer and the IPAQ (International Physical Activity Questionnaire). Data was analyzed using a repeated measures ANOVA (intention to treat).
Results: 30 patients with non-CF bronchiectasis (15 in each group) were included, without differences in clinical variables between groups. After intervention, a significant percentage of patients in the supplement group increased their average physical activity according to the IPAQ after 3 and 6 months. Significant differences depending on type of intervention were not observed. A slight increase in average moderate intensity physical activity measured by accelerometer was observed at 3 and 6 months, but it did not reach statistical significance.
Conclusions: PR, along with nutritional supplements, in non-CF bronchiectasis patients increased the level of physical activity measured by the IPAQ (at 3 and 6 months). However, it did not reach statistical significance according to accelerometer measurements. Further studies are needed to evaluate the validity of the different measurement instruments.